BUTCH, ANTHONY, W (Total 5 Patents Found)

The present disclosure concerns methods for recombinantly producing functional ataxia-telangiectasia (ATM) protein, methods for isolating recombinant functional ATM protein, and uses of ATM protein including diagnosing a patient for A-T and/or susceptibility to various conditions including cancer, particularly breast c...
The present disclosure concerns methods for recombinantly producing functional ataxia-telangiectasia (ATM) protein, methods for isolating recombinant functional ATM protein, and uses of ATM protein including diagnosing a patient for A-T and/or susceptibility to various conditions including cancer, particularly breast c...
La présente invention porte sur des procédés pour effectuer une analyse pour identifier des homozygotes ou des hétérozygotes du syndrome de Louis-Bar. Certains modes de réalisation comprennent l'utilisation d'une analyse de kinase du syndrome de Louis-Bar (ATM) à base de cytométrie en flux rapide qui me...
The present disclosure concerns methods for recombinantly producing functional ataxia-telangiectasia (ATM) protein, methods for isolating recombinant functional ATM protein, and uses of ATM protein including diagnosing a patient for A-T and/or susceptibility to various conditions including cancer, particularly breast c...
The present disclosure relates to methods for performing an assay to identify ataxia-telangiectasia homozygotes or heterozygotes. Some embodiments include the use of a rapid flow cytometry-based ataxiatelangiectasia (ATM) kinase assay that measures ATM-dependent phosphorylation of SMC1 following DNA damage....